S+SLAM-TIA is a research project evaluating the effect of translation of an evidence based stroke prevention education and exercise program into the Hunter New England Local Health District (HNE LHD) health service.
moreS+SLAM-TIA is a research project evaluating the effect of translation of an evidence based stroke prevention education and exercise program into the Hunter New England Local Health District (HNE LHD) health service.
moreNeil Spratt, Dr Damian McLeod
Ischaemic stroke, caused by blood clot blocking an artery to the brain, is a leading cause of death and disability. In around 10% of patients the stroke enlarges in the first 24-48 h (stroke-in-progression). Typically, these are people who arrive with mild or rapidly improving stroke symptoms, but most end up with long-term disability. There is no effective treatment, in part because for the last few decades we have been wrong about the cause for stroke progression, so have been trying to treat the wrong mechanism.
moreThe 470,000 Australians living with stroke are at high risk of developing cognitive deficits and vascular dementia. There are currently no generally accepted therapeutic interventions for improving cognition post-stroke.
moreJoshua Atkins
Special grant for Josh Atkins to travel to France to speak at a conference and then go on to make some important collaborations in both France and UK in bioinformatics and personalised medicine.
moreCatherine Hidson
Co-sponsorship for Dr Terri Armstrong to speak at 11th COGNO Scientific Meeting in Brisbane 7-9 October 2018.
moreMultiple myeloma (MM) is a cancer of plasma cells, which are mature white blood cells within the bone marrow. The disease causes bone pain, fractures, infections, anaemia and renal failure. It typically affects people over the age of 60, with about 1700 new diagnoses each year in Australia.[1] It is incurable and carries a life expectancy of 2-7 years depending on the aggressiveness of the tumour cells.
moreDr Anoop Enjeti, Ms Nadine Berry
Ovarian cancer is usually treated with a chemotherapy drug called cisplatin which works by damaging DNA so much that the tumour cells die. Cisplatin is used to treat a wide variety of tumours in addition to ovarian cancer including, testicular, head and neck and non-small cell lung cancer. In addition, it forms the basis of most combined treatment regimes (where 2 or more drugs are used in combination). The downside to cisplatin is that it is extremely toxic and although some patients benefit substantially from treatment, a large proportion suffer the toxic side effects without any therapeutic benefit. We are aiming to develop a personal test to determine if cisplatin is likely to be effective for an individual’s ovarian cancer, so that the toxic side effects can be avoided if the drug is not going to work.
moreMarina Kastelan
Neuro Oncology is a niche area with around 500 newly diagnosed GLioma patients per year in NSW; however the care and support needs for this patient group are great, with high carer burden.
moreDr Anthony Proietto
The CN2 will provide expert clinical consultancy to support high level care coordination for brain cancer patients requiring complex management.
moreProfessor Ronald Plotnikoff, Wendy Brown, Kerry Courneya, Ronald Sigal, Associate Professor Erica James, Professor David Lubans, Kristen Cohen
People who are 'at risk' of type 2 diabetes, or have pre diabetes, or have type 2 diabetes comprise a significant proportion of the Australian population and this health issue in increasing at a very significant rate.
moreGlobally, nearly 1% of all pregnancies end in stillbirth (3 million each year). The magnitude and gravity of stillbirth is such that in 2011 an entire Lancet series was devoted to it and urged a strong call to action, concluding that greater knowledge of causes is a key health priority. In Australia, stillbirth accounts for around 70% of all perinatal deaths (7 deaths per day) and is nearly 40 times more common than Sudden Infant Death Syndrome. Existing knowledge has had no impact on reducing the stillbirth rate, and a 2013 BMJ review of the UK data on stillbirth concluded ""preventive strategies need to focus on improving antenatal detection."
moreBruce King, Graham Goodwin
Funding to support the Gomeroi gaaynggal Community ArtsHealth running in Tamworth - covers art consumables which brings participants into the centre to participate in health screening and research being conducted.
moreA/Prof Bruce King
Patrick Oakley
The New South Wales tablelands are a known region to have low environmental iodine in soil. This is similar to other regions around the world such as the Himalayas and Papua New Guinea. This is known to impact the food grown locally. The introduction of iodised salt into diets has assisted in reducing the impact. However, modern diets with a reliance on processed foods that are not required to use iodised salt, has left "modern diets" deficient in iodine.
moreLaureate Professor Roger Smith AM, Mrs Lee Dedman
Travel funding to Wellington NZ to learn 3D animation 13/4/2018-25/4/2018
moreAlice Grady
Internationally, 41 million children aged 0-5 years were overweight or obese in 2016(1). Poor nutrition is one of the most important risk factors for the development of obesity(2). As early childhood is a formative time for developing healthy eating behaviours, population health strategies that support children to eat better are of upmost importance(3).
moreAsthma affects one in eight children in Australia and is the leading cause of hospitalisations and emergency visits, with an estimated annual health care cost of more than 24 billion Australian dollars in 2015. Asthma is the most common medical complication in pregnancy and is strongly associated with the development of childhood asthma. ntion strategy for asthma.
moreLaureate Professor Robert Sanson-Fisher, Dr Mariko Carey, Dr Elise Mansfield, Dr Chris Oldmeadow, Ms Natalie Dodd
Despite innovative programs to increase colorectal cancer (CRC) screening amongst people >50 years of age, such the National Bowel Cancer Screening Program (NBCSP), current screening rates are low.
moreCystic Fibrosis (CF) is the most common life threatening genetic condition in Australia and affects many organs, in particular the lungs, and is one of the 3 most common reasons for a lung transplant. Although improved treatments have seen life expectancy extended, the average life expectancy of a CF patient in Australia is still only 38.
moreUrinary leakage in the daytime, feeling of urgency to urinate and frequent urination are common and often incapacitating problems in school-aged children. If affects 5-10% of healthy, otherwise normal children and significantly disrupts their day-to-day life and learning.(6,7) This has consequences for mental health and healthy development.
moreSmoking leads to lung inflammation that causes emphysema - a major health problem in Australia. Emphysema progressively declines even if smoking stops and there are no treatments. Recently changes in gut microbes have been linked to inducing or protecting against inflammation in the gut and lung. Thus we may be able to control inflammation by modifying these gut microbiomes. We may be able to ingest specific microbes or use specific antibiotics or other factors as new treatments for emphysema.
moreAsthma is a common condition that causes tightness in the chest, coughing and wheeze and makes it difficult to breath. Around 10.2% of the Australian population (approximately 2.3 million people) have asthma, it is a major health problem here in Australia and worldwide.
moreDr Andrew Reid, Mr Punnam Veerati, Associate Professor Chris Grainge
Bronchoconstriction is a cardinal feature of asthma, generating mechanical stresses within the airways including cell compression and increased shear stress due to increased air-flow.
moreCurrently there is a two year wait list to see an Ear Nose & Throat (ENT) specialist in the Hunter New England district, the largest health district in NSW with one ENT specialist clinic. Lack of access to specialist health care creates a significant disparity in health outcomes for Indigenous and rural patients. Serious health complications, including deafness lead to socioeconomic disadvantage.
moreUsing computer vision to match the faces of children with undiagnosed intellectual disability.
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