Cardiovascular Disease is the leading cause of death worldwide and the Hunter Region has one of the highest rates of heart disease in Australia.

Recently the research team has identified a new protein called fibulin-3 which is expressed in the ageing heart. An analysis of the impact of fibulin-3 on the heart kidneys, muscle and skin will be performed using a number of techniques including 3D tissue clearing and light sheet microscopy in a gene knockout model. This study will provide invaluable information for further studies on the role of fibulin-3 in heart attack and heart failure models.

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