The role of the microbiome (gut bacteria) in the development of food allergy

Food allergy affects 1 in 10 infants and 1 in 100 adults in Australia. It is an immune driven response ranging from mild rashes, to gastrointestinal inflammation to life-threatening systemic responses (anaphylaxis). Recent evidence suggests that disruption of the intestinal microbiome may influence the development of food allergy. This study will examine the role of antibiotic disruption of the intestinal microbiome in the progression and pathogenesis of food allergy.  Is early life antibiotic exposure is important in later food allergy reactions and can replenishing specific populations of the microbiome reduce food allergy severity.

Researchers 

Dr Simon Keely, Jay Horvat 

Project type 
Project Grant
Year of funding 
2013