Many studies have demonstrated that obesity increases asthma risk. However, the mechanisms behind this association are uncertain. We are interested obesity as a cause of inflammation, as this may be contributing to asthma development and progression. In Feb 2009, we enrolled a PhD student, who is commencing a project exploring the relationship between obesity, inflammation and asthma in children. This student will also examine the effect of weight loss on markers of inflammation and clinical outcomes in children with asthma. We are seeking funding to cover the consumables for this students project.
Asthma prevelance has increased in many western countries over recent decades. Currently, 1 in 6 children in Australia are affected by the disease. Over this time, obesity rates have also increased, and obesity now effects around 10% of Australian children.