Category: News & Articles
... product chemistry within our lab, to find plant-based anti-cancer drugs. By Dr Chris Scarlett There are no two ways about it. Pancreatic ... derived from natural products (as critically >50% of all anti-cancer drugs are derived from natural products). Importantly, plant-derived anti-cancer drugs have been developed and are in use clinically. For example the ...
Category: News & Articles
... researchers who made them. Doan’s research focuses on identifying drugs that protect the heart from toxic side effects of cancer therapies ... conditions than the rest of the population as the use of anti-cancer drugs can be toxic to the heart. This means over two million ...
Category: News & Articles
... potentially be effective for other types of cancer. “Anti-cancer drugs typically work by targeting proteins, making our finding highly ... a therapeutic vulnerability. “We knew if we could find or develop drugs that targeted the proteins active or present in the leukaemia ...
Category: News & Articles
... new treatment strategy will allow us to better design anti-cancer drugs. What do you hope to achieve in the future? The use of naturally ...
Category: News & Articles
... treatment. The team used its DMG models to test the effect of the drugs in combination, finding them beneficial and safe, progressing the ... stages (irrespective of past treatments) and is ‘adaptive’ - new drugs or approaches can be evaluated as additional arms of the trial as ... of using them in combination. “We are continuing to study these drugs in our lab-based DMG models so we can understand how to improve ...
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... to reduce severe toxicity. Fluoropyrimidines and irinotecan are anticancer drugs which, even at standard doses, cause severe toxicity leading to ... that mutations in the genes responsible for metabolism of these drugs are responsible for toxicity in a proportion of cases. Professor ...
Category: News & Articles
... and breast cancers – but it can be reactivated using certain drugs – and these proteins can then potentially be used to kill cancer ... discovery, they are able to take the next step – develop better drugs to treat the cancers. The ultimate aim of Nikki’s work is to ... treatment a patient needs; and to arm the clinicians with the right drugs to treat those patients. With both breast cancer and AML, there ...
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... need to understand the mechanism so we can find ways to add other drugs that amplify the effect, and week by week we’re getting more ...
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... focused on a range of chemicals released from immune cells. In fact drugs that target one of these chemicals (TNFά) offer some relief to ... ineffective. The design of new and more effective anti-arrhythmic drugs is hampered by the lack of an understanding how an ideal drug ... anti-arrhythmic drug strategy; and be a foundation for the design of drugs to control ventricular arrhythmias in coronary artery disease. ...
Category: News & Articles
... to assist cancer researchers in the development of new anti-cancer drugs, ensuring the best outcomes for patients. The Ramaciotti ... to assist cancer researchers in the development of new anti-cancer drugs, ensuring the best outcomes for patients. The Ramaciotti ...