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Leukaemia
Category: Research
Leukaemia is a cancer of the blood or bone marrow involving abnormal ... every year. (Source – Australian Institute of Health and Welfare ) Acute Lymphoblastic Leukaemia (ALL) is one of the most deadly and most ... outcomes of patients with leukaemia. Another type of leukaemia, Acute myeloid leukaemia (AML), is a rapidly progressing blood cancer ...
Defining the role of shwachman-bodien diamond syndrome protein (SBDS) in PP2A inhibition in acute myeloid leukaemia (AML)
Category: Research
A new treatment for acute myeloid leukaemia Acute myeloid leukaemia (AML) is the most common and deadly type of adult leukaemia, with a ...
Improving the effectiveness of a new treatment for acute myeloid leukaemia (AML)
Category: Research
Acute myeloid leukaemia (AML) is the most common acute leukaemia affecting adults, and accounts ...
Targeting BAALC as a new treatment for acute myeloid leukaemia
Category: Research
Improving survival from Acute myeloid leukaemia (AML) with new therapies Acute myeloid leukaemia (AML) is the ...
Identifying novel therapeutic targets for the treatment of Acute Myeloid Leukaemia
Category: Research
Finding the ‘disease-causing’ mutations and proteins in Acute Myeloid Leukaemia to develop new treatment strategies. Acute Myeloid Leukaemia ...
Developing new treatments for resistance in acute myeloid leukaemia
Category: Research
Treatment for the most common and deadly form of blood cancer (acute myeloid leukaemia) hasn’t changed in over 40 years. New treatments fail ...
Receptor tyrosine kinase mutations in acute myeloid leukaemia promote PP2A and p53 inhibition through the phosphorylation of SBDS
Category: Research
AML (acute myeloid leukemia) is a very aggressive form of leukemia. ... future. Research Receptor tyrosine kinase mutations in acute myeloid leukaemia promote PP2A and p53 inhibition through the phosphorylation of ...
Re-purposing PARP inhibitors to treat childhood leukaemias
Category: Research
... is the most common cause of childhood disease-related deaths, with leukaemia the most common childhood cancer in Australia. The two most common forms of leukaemia in children are acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML). Whilst remission is achievable in over 95% of ...
Targeting DNA repair for the improved treatment of blood cancers
Category: Research
Acute myeloid leukaemia (AML) is the most common form of acute leukaemia, and it has the lowest ...
Determining the mechanisms underpinning leukaemic transformation for children suffering from Shwachman-Diamond Syndrome (SDS)
Category: Research
... to sepsis, organ failure and most frequently the development of leukaemia.  At the current time, detailed knowledge about disease ... protein is an inhibitor of the tumour suppressor protein, PP2A, in acute myeloid leukaemia (AML), the deadliest form of leukaemia (the results of ...