Category: News & Articles
... effectiveness for COVID-19. However, there are multiple drug treatment options, and combinations, that may be effective. Laboratory ... Tong. “We have designed the trial so that it’s responsive and adaptive. This means that if one of the drugs is proving to be effective, we can adapt the trial to focus on that treatment. “Conversely, if a drug isn’t effective, or is causing ...
Category: News & Articles
... 2018, and is now leading the scientific arm that has developed treatment strategies combining targeted therapies for this most deadly ... to improve outcomes using a single drug approach. DMG-ACT, is an adaptive combination therapy clinical trial that combines drugs which ... While it is early days, it is exciting to see the emergence of new treatment strategies for a disease which until now clinicians have had ...
Category: Researcher Profiles
... imaging for planning treatments to better define the targets for treatment and for verifying that the treatments are delivered accurately ... research? My major focus is on translating the work we do to other treatment centres and patients in general for improved care. This is ... of MRI scans directly for radiation oncology prostate planning and adaptive treatment. There is currently great international interest in ...
Category: Researcher Profiles
... stroke and brain injury. Maternal cognitive control on development of adaptive behavior patterns in offspring. Link between cognitive control and anxiety on adaptive behavior patterns in childhood, young and late adulthood. My ... new insights about multidisciplinary approaches to prevention and treatment of mental and physical illness. What would be the ultimate ...
Category: Research
... when stressed but melanoma cells don’t because they have developed adaptive mechanisms to stress conditions. Instead of dying, melanoma ... melanomas which may for the first time, provide an effective treatment for patients with advanced skin cancer. Breakthroughs by ... unlock the doors that lead to reliable and effective prevention and treatment of one of the nation’s biggest killers. Research Melanoma ...
Category: Researcher Profiles
... of melanoma in the world. However, there is currently no curative treatment once the disease spreads beyond the original site. To address ... a focused theme of “overcoming resistance of metastatic melanoma to treatment” for more than 10 years. What would be the ultimate goal for ... three PhD students. Dr Jiang pioneered studies on “understanding adaptive mechanisms of melanoma cells to endoplasmic reticulum (ER) ...
Category: News & Articles
... Professor Davis said. ASCOT is also designed to be responsive and adaptive, which means that new drugs can be added if they show promise. ... (efficacy) and, more importantly, how safe they are for frontline treatment. “With the ASCOT trial we’re testing drugs that we know ...
Category: News & Articles
... and balance. Palliative radiotherapy is the only established treatment, with families advised their child is expected to survive nine ... combination with a second drug, ‘paxalisib’ and standard of care treatment, radiotherapy. How the research transpired in the quest to ... at all disease stages (irrespective of past treatments) and is ‘adaptive’ - new drugs or approaches can be evaluated as additional ...
Category: General
... and have this reach clinical practice. We will likely need multiple treatment strategies, as a ‘one size fits all’ approach would be ... the chance of new viruses emerging and differences in response to treatment between different people. Biography Dr Jason Girkin completed ... the lung, antiviral responses and novel therapeutics for prophylactic treatment of viral-induced disease. Jason’s contribution to this field ...
Category: News & Articles
... of PMS, and it utilises an exciting new clinical trial design called adaptive clinical trials. An adaptive clinical trial (ACT) uses a new design whereby interim ...
