Category: Research
... sufferers. Our research investigates the structure and function of epithelium in asthma. The epithelium is the thin tissue lining the outer layer of airway surface and is the first protective barrier between inhaled ... on epithelial cells proliferation or differentiation hence restoring airway epithelium integrity. In order to achieve our goals we use the ...
Category: General
... to study RV infections for the exacerbation work proposed. The airway epithelium is the site of RV infection and is now the focus of research ... underpin disease. However it is still unclear how viral infection of airway epithelium activates type-2 immunity to cause an exacerbation. We ...
Category: Researcher Profiles
... group has developed expertise in identifying respiratory viruses in airway secretions and developing an in-vitro cell culture model of infection. The role of the airway epithelium in innate immunity and inflammation in the context of ...
Category: Research
Cystic fibrosis (CF) is the most common genetically-inherited life-shortening chronic illness affecting young Australians today. A baby is born with cystic fibrosis every four days (Source – Better Health Channel). It primarily affects the respiratory system with recurrent infections and the risk for lung damage long term, among other symptoms.
Category: Researcher Profiles
... what makes an asthmatic lung faulty. To be more precise I look at the airway epithelium which is the thin barrier protecting all of us from the ... air we breathe. A key interest of mine is trying to understand how airway epithelial cells from an asthmatic individual are inherently ...
Category: Researcher Profiles
... conditions such as asthma and COPD the involvement of virus infected airway (epithelial) cells on activation of allergic inflammation understanding how rhinoviruses replicate in airway epithelial cells to discover new targets for anti-viral ... asthma and COPD exacerbations. Rhinovirus, asthma, respiratory epithelium, innate immunity, allergic inflammation, asthma exacerbation, ...
Category: Researcher Profiles
... cells that line the lungs. We can study a model of the lung epithelium using air-liquid interface cell culture. This allows the ... all of these parts together, I examine the first response of the lung epithelium to virus infection or the innate immune response. This is ... exacerbations from a common cold. Specialised/Technical Skills Human airway epithelial models Virus growth, purification and titration ...
Category: Researcher Profiles
... for a year. I then returned as a PhD student working out how the epithelium regulated smooth muscle contraction and how this is ... University of British Columbia (UBC) as the Canada Research Chair in Airway Disease. He was then recruited back to Australia in 2013 and is ... biologist with an international reputation in the area of lung and airway remodelling. His research career has focused on understanding how ...
Category: News & Articles
... able to use cells from human donors and re-grow the structure of the airway surface, the epithelium, to recreate the first line of defense against respiratory viruses.This model of the human airway was key to researchers showing that INNA-X can directly activate ...
Category: General
... carved an international research niche by focusing on understanding airway inflammation caused by neutrophils, which are white blood cells ... a novel inflammatory mechanism that results in neutrophilic airway inflammation (innate immune dysfunction), which led to another ... Fatemeh Moheimani | A novel approach in restoring the airway epithelium integrity in asthmatics JHH Charitable Trust Anthony Quail | ...
