Category: General
... carved an international research niche by focusing on understanding airway inflammation caused by neutrophils, which are white blood cells that ... a novel inflammatory mechanism that results in neutrophilic airway inflammation (innate immune dysfunction), which led to another ...
Category: Research
Smoking leads to lung inflammation that causes emphysema - a major health problem in ... in gut microbes have been linked to inducing or protecting against inflammation in the gut and lung. Thus we may be able to control ... of COPD. Conversely the non-smoking models start to show signs of airway inflammation. We have now identified 2 virtually unknown bacteria ...
Category: Research
Smoking leads to lung inflammation that causes emphysema - a major health problem in ... in gut microbes have been linked to inducing or protecting against inflammation in the gut and lung. Thus we may be able to control ... of COPD. Conversely the non-smoking models start to show signs of airway inflammation. We have now identified 2 virtually unknown bacteria ...
Category: Research
... other respiratory diseases are often linked to the immune system and inflammation. This is because the immune system is thought to be a regulator of asthma and airways inflammation by producing too many immune factors in response to a ... factors have been identified in the signalling pathways that induce inflammation, as well as chlamydia lung infections in newborns, a major ...
Category: Research
Smoking leads to lung inflammation that causes emphysema - a major health problem in ... in gut microbes have been linked to inducing or protecting against inflammation in the gut and lung. Thus we may be able to control ... of COPD. Conversely the non-smoking mice start to show signs of airway inflammation. We have now identified 2 virtually unknown bacteria ...
Category: News & Articles
... worldwide, continues to rise. The disease is characterised by chronic airway inflammation and emphysema, which lead to breathlessness and respiratory ... in the case of smokers, the mast cells respond inappropriately to airway inflammation and actually cause tissue damage.” The lab team ...
Category: News & Articles
... have a defect in the antiviral responses of the cells that line the airway walls. Why is this significant? Virus induced asthma attacks are ... my clinical research and our current study will examine the effect of inflammation of the airways in worsening lung disease in adults and ... lung diseases. We aim to detect important differences in the ways the airway cells react to triggers of lung inflammation, thereby giving us a ...
Category: Research
... and previously associated with the development of allergic airways inflammation. Our aim is to build on these observations and characterise ... to boost antiviral IFN responses and limit exaggerated RV-induced inflammation associated with exacerbations. OVERALL HYPOTHESIS: TLR7 ... to RV that limits viral replication and Th2 dominated airways inflammation. Research Molecular and cellular characterisation of TLR7 ...
Category: Researcher Profiles
... was internationally recognized as the first to demonstrate that inflammation appears to be driving the association between obesity and ... training resulting in a highly significant halving of asthmatic airway inflammation (sputum eosinophils) and an improvement in asthma-related ...
Category: News & Articles
... as the trigger for a complex biological cascade that drives inflammation and the pathogenesis of severe asthma. “Steroid ... various microRNAs that are known to bind to different genes and fuel inflammation. “Just before we gave a second allergen dose to induce a ... then causes an increase in the enzyme PI3 kinase, driving further inflammation, which finally inhibits a molecule known as HDAC2 [Histone ...
