Category: News & Articles
... they reproduce. However the specks retain their ability to trigger inflammation even after the demise of the original cell. “Humans ... it’s active all the time, it drives this continual cycle of inflammation … it becomes exaggerated and uncontrollable, which could ... for Asthma and Respiratory Disease, and Leader of the Asthma and Airways Research Group in HMRI’s VIVA Program. HMRI is a partnership ...
Category: Research
... oxide concentration (FeNO) as a non-invasive surrogate marker for airways inflammation). Bronchiolitis is the most common and severe virus-induced ... related to antiviral host responses and the development of atopy and airways inflammation in childhood, which are all considered as crucial ...
Category: Research
... The Growing into Asthma Study: Wheezing prevalance and markers of airways inflammation in preschoolers born to mothers in asthma exacerbations in ...
Category: Researcher Profiles
... are your research interests? My research has a focus on understanding inflammation in airways disease and in particular neutrophilic inflammation. Neutrophils ... in fighting invasions such as infection. In some patients with airways disease, neutrophils persist in the airways and this can result ...
Category: General
... activation of type-2 immunity is an important driver of pulmonary inflammation during an asthma exacerbation. Epithelial regulation of ... by corticosteroids and activates type-2 immunity leading to increased airways inflammation and worsening of asthma symptoms. We therefore aim ... infection of bronchial epithelium. General Specifically targeting the airways to prevent virus-induced asthma attacks ...
Category: Research
... The role of viral infections in the exacerbation of asthma and airways diseases such as COPD and cystic fibrosis is a research strength ... advised to eat a high energy diet as the chronic secretions in the airways can impede normal digestion and nutrients are often lost before ... interferon-β) in asthmatics which may interfere with viruses in the airways, potentially providing some relief for the persistent infections ...
Category: Researcher Profiles
... of the innate immune system in the pathogenesis of steroid-resistant inflammation in asthma. His research addresses an unmet need globally ... widely to treat many inflammatory diseases, especially those of the airways, skin and joints. However, under some conditions inflammation is poorly controlled by glucocorticoids, and the mechanisms ...
Category: Researcher Profiles
... develop gene-expression biomarker signatures for predicting airway inflammation, treatment responses and future risk of exacerbations of airways disease. Better diagnostic tests will inform clinicians on what ... them. To understand the mechanisms of neutrophilic inflammation in airways disease (neutrophils are a type of white blood cell) so we can ...
Category: News & Articles
... have discovered a protein that induces both stiffening and inflammation in the airways of the lung, causing severe and chronic respiratory illness. ... a protein that induces both stiffening and inflammation in the airways of the lung, causing severe and chronic respiratory illness. ...
Category: Researcher Profiles
... in the investigation and therapeutic targeting of infection and inflammation-induced diseases of the respiratory, reproductive and ... His major focus is on asthma and respiratory diseases. Excessive inflammation and dysregulated immune responses play a key role in asthma ... and different types of infections affect immune responses in the airways of people with asthma to drive more severe, poorly controlled ...