Category: Research
... The role of viral infections in the exacerbation of asthma and airways diseases such as COPD and cystic fibrosis is a research strength ... advised to eat a high energy diet as the chronic secretions in the airways can impede normal digestion and nutrients are often lost before ... interferon-β) in asthmatics which may interfere with viruses in the airways, potentially providing some relief for the persistent infections ...
Category: Research
... and wellbeing. We study asthma, chronic obstructive pulmonary disease (COPD), vocal cord dysfunction, nose and upper airway disorders, ... the whole respiratory system, including the upper, middle and lower airways and the lungs. Disorders of this system account for a large ... as from bushfires) an abnormal distribution of the microbiota and an allergic immune response, are interrelated and potentially modifiable ...
Category: Research
Asthma affects up to 10% of Australians and is the most common chronic disease complication during pregnancy. Poor asthma control during ... oxide concentration (FeNO) as a non-invasive surrogate marker for airways inflammation). Bronchiolitis is the most common and severe ... and recurrent LRTI are associated with a considerable risk to have allergic asthma in childhood, particular when they occur in infants at ...
Category: Researcher Profiles
... of Newcastle’s Priority Research Centre for Asthma and Respiratory Disease. He is also a visiting Professor at highly prestigious ... and genetic factors can affect the functioning of the lungs and airways and ultimately contribute to the development of respiratory ... and respiratory infections. Paul Foster, asthma research, respiratory disease research, VIVA Paul Foster - Asthma and Respiratory Disease ...
Category: General
... them to abnormal differentiation and repair and these appear early in disease development. Another finding is that asthmatic epithelium can ... of type-2 immunity: Most children and around 50% of adults have allergic asthma. Type-2 immunity is upregulated in allergic asthma and ... by corticosteroids and activates type-2 immunity leading to increased airways inflammation and worsening of asthma symptoms. We therefore aim ...
Category: Research
... physicians and epidemiologists to investigate diseases of the airways. This includes extensive research into the role of infections ... multidisciplinary study into the cellular and molecular aspects of allergic diseases and airways inflammation and also in translational ... pregnancy and the accurate diagnosis of chronic obstructive pulmonary disease (COPD). "What we have is diversity and common interest… The ...
Category: Researcher Profiles
... treatment. Assessment, characterisation and management of difficult airways disease. This includes severe asthma, but I am interested in extending ... Professor Wark has established a direct link between uncontrolled allergic inflammation and impaired antiviral responses in asthma. He ...
Category: Researcher Profiles
... future research is to investigate the role of host innate immunity in allergic and infectious diseases, and to develop better approaches to ... in both the Priority Research Centre for Asthma and Respiratory Disease and the VIVA program. His research focuses on the role of the ... widely to treat many inflammatory diseases, especially those of the airways, skin and joints. However, under some conditions inflammation is ...
Category: Researcher Profiles
... interested in the mechanisms responsible for the early development of allergic diseases. Asthma : The development of asthma in early life is ... developing new treatments and less invasive methods of diagnosis and disease monitoring. Why did you get into research? Since a young age I ... signalling pathways (normal regulators of cell death) in the allergic airways as novel treatment strategies for allergic asthma. Since ...
Category: Researcher Profiles
... of virus infected airway (epithelial) cells on activation of allergic inflammation understanding how rhinoviruses replicate in airway ... within the Section of Virology and more recently within the Airway Disease Infection Section, Faculty of Medicine, Imperial College London. ... a model of rhinovirus infection and exacerbation of allergic airways disease which generated an immense amount of interest within the ...
