Category: Researcher Profiles
... of new treatments and understandings of a range of respiratory diseases. Why did you get into research? To discover fundamental ... biological systems, which are relevant to finding new treatments for diseases. Early in my career I received advice from a close friend’s ... to research would ensure new treatments for patients with respiratory diseases. Another major goal is to continue research in my field through ...
Category: Research
... role of viral infections in the exacerbation of asthma and airways diseases such as COPD and cystic fibrosis is a research strength for ...
Category: Researcher Profiles
... of virus infected airway (epithelial) cells on activation of allergic inflammation understanding how rhinoviruses replicate in airway ... become clear that viruses play a crucial role in chronic respiratory diseases such as asthma. The relationship between virus and man is ... describing a model of rhinovirus infection and exacerbation of allergic airways disease which generated an immense amount of interest ...
Category: Research
... respiratory physicians and epidemiologists to investigate diseases of the airways. This includes extensive research into the role ... and methods of developing new vaccines for the treatment of diseases such as cancer. The HMRI VIVA research program links two of ... multidisciplinary study into the cellular and molecular aspects of allergic diseases and airways inflammation and also in translational ...
Category: Researcher Profiles
... interested in the mechanisms responsible for the early development of allergic diseases. Asthma : The development of asthma in early life is strongly ... TRAIL signalling pathways (normal regulators of cell death) in the allergic airways as novel treatment strategies for allergic asthma. ...
Category: Researcher Profiles
... of innate immune cells and in the pathogenesis of respiratory diseases. Novel therapeutic approaches involving gene modulation. Why ... future research is to investigate the role of host innate immunity in allergic and infectious diseases, and to develop better approaches to ... this research program and established experimental models of allergic airway diseases, acute respiratory infection and severe and ...
Category: General
... the greatest single precipitant of acute exacerbation of both diseases. For this reason we believe it important to study RV infections ... of type-2 immunity: Most children and around 50% of adults have allergic asthma. Type-2 immunity is upregulated in allergic asthma and is defined by production of IL-4, IL-5, IL9 and ...
Category: Research
... Furthermore, the major focus in asthma research has been on the allergic inflammatory aspects. However, not everyone who suffers from an ... and Asthma (VIVA) and Priority Research Centre Asthma and Respiratory Diseases at the University of Newcastle. Research A novel approach in ...
Category: Researcher Profiles
... in determining different inflammatory phenotypes (subgroups) in these diseases and how this may influence treatment. Assessment, ... Professor Wark has established a direct link between uncontrolled allergic inflammation and impaired antiviral responses in asthma. He ...
