Category: News & Articles
... need to understand the mechanism so we can find ways to add other drugs that amplify the effect, and week by week we’re getting more ...
Category: News & Articles
... focused on a range of chemicals released from immune cells. In fact drugs that target one of these chemicals (TNFά) offer some relief to ... ineffective. The design of new and more effective anti-arrhythmic drugs is hampered by the lack of an understanding how an ideal drug ... anti-arrhythmic drug strategy; and be a foundation for the design of drugs to control ventricular arrhythmias in coronary artery disease. ...
Category: Research
... with loss of PPP2R2A are highly sensitive to two specific classes of anticancer drugs: PARP inhibitors, and PP2A activating drugs. This project will test whether tumours with PPP2R2A loss will ...
Category: News & Articles
... to assist cancer researchers in the development of new anti-cancer drugs, ensuring the best outcomes for patients. The Ramaciotti ... to assist cancer researchers in the development of new anti-cancer drugs, ensuring the best outcomes for patients. The Ramaciotti ...
Category: News & Articles
... off of PP2A in AML, the team are able to target this protein using drugs to restore PP2A activity, killing the tumour cells. Importantly it ...
Category: News & Articles
... benefit patients. “There’s still a lot of unmet need. KEYTRUDA drugs currently have response rates in the order of 30 to 50 per cent ...
Category: Research
Fluoropyrimidines (5-FU and capecitabine) are anticancer drugs commonly used in a range of cancers including oesophageal, gastric ...
Category: Research
... In 2014, researchers reported a new combination of anti-cancer drugs and radiation which was successful in treating men with ...
Category: Researcher Profiles
... and change over time. Ultimately, my goal is to design more effective drugs that prevent cancer or prevent it coming back in patients after ... cancer patients, in order to better understand the actions of these drugs and to identify markers that predict treatment response. This will ...
Category: News & Articles
... findings hold true at the 10-year patient follow-up in 2017. As all drugs used in the trials are already in widespread use, these treatments ...