Category: News & Articles
... the airways of people with asthma are more susceptible to infection with the cold virus.
Researchers found that asthmatic airway cells and immune cells responded poorly to infection with the cold virus. Participants who recorded the greatest worsening ... release of antiviral proteins (interferons) in response to infection.
“Our research indicates that asthmatics have a deficient early ...
The HMRI Viruses, Infections/Immunity, Vaccines and Asthma (VIVA) Research Program brings together basic laboratory scientists, clinical researchers, respiratory physicians and epidemiologists to investigate diseases of the airways.
This includes extensive research into the role of infections and inflammation in the development of asthma and other respiratory problems, including during pregnancy, in cystic fibrosis patients and even in the gut. The VIVA group also researches the biology of viruses, how they can affect respiration and methods of developing new vaccines for the treatment of diseases such as cancer.
... mucous in the gut functions under normal circumstances, when infection is present and when there is a reduced oxygen supply. They are also ...
Identification of Predictors of Infection in Pregnant Women / IgA Responses to infection in Pregnancy ...
... subjects with COPD are so susceptible to the effects of RV infection. We will determine if immunosenescence (an age dependent decrease in ... does this affect the ability of these cells to respond to infection and repair.
Immunosenescence in chronic ...
... aim of this research project is to determine if bacterial infection could be causing an increase in the activation of tyrosine ... researchers will:
1) Investigate the effect of bacterial infection (using the LPS molecule) on the regulation of dopamine synthesis in ... brain regions.
2) Investigate the effect of bacterial infection on the activation of microglia (immune defence cells) in the ...
Category: Researcher Profiles
... furthered the understanding of the deleterious effects of infection in early life and how these infections have long-term consequences ... and immune systems. More recently Dr Starkey has modeled infection-induced severe asthma and emphysema and is identifying strategies for ... Heart and Lung Institute Imperial College, Institute of Infection and Immunity Cardiff University and University of London. He has been ...
Category: Researcher Profiles
... your research interests?
Effects of inflammation and infection on blood cell development and immune responses.
Effects of inflammation and infection on bone cell development and bone structure.
Regulation of bone ... immune cells develop and what controls their responses to infection.
What would be the ultimate goal for your research?
On a ...
Early-life lung infections, caused by respiratory bacteria and viruses, lead to permanent alterations in lung structure and function that predispose children to the development of chronic lung diseases such as asthma and emphysema in later-life.
... bacteria even in healthy state and in the absence of any infection.(2) In adult women, changes in the quantity and type of these ... abnormalities in the bacteria present in the absence of infection in the urine and feces (microbiome) in children with bladder bowel ...