Category: Research
Research MicroRNA and antagomirs in the regulation and suppression of interferon (IFN)-g and lipopolysaccharide (LPS) induced ...
Category: News & Articles
... cold. The international Phase 2 trial of a synthetic anti-viral ‘interferon’, inhaled via a nebuliser, proved most effective in helping ... they were then assessed within 24 hours and administered either the interferon or a placebo. The results, published in the American Journal ... looking for biomarker signatures. Professor Wark believes nebulised interferon could be applied to other patients with chronic respiratory ...
Category: Research
... of asthma exacerbations, which may be linked to an impaired antiviral interferon (IFN) response in asthmatics. RV is a single stranded (ss) ... attenuated RV clearance from the lungs. TLR7 deficiency also impaired interferon regulatory factor (IRF) 7 expression a master regulator of interferon responses in virus-induced asthma exacerbation in children ...
Category: Researcher Profiles
... replication within 24 hours of infection and also induced a strong interferon response from the epithelial cells. In contrast, OC43 reached ... this infection did not resolve. Interestingly OC43 did not induce an interferon response from the cells and this may suggest why its ...
Category: Researcher Profiles
... common cold) with reduced release of a key immune response molecule, interferon (IFN)-β. The seminal finding that asthma can be associated with impaired interferon responses to rhinovirus has led to an international ...
Category: News & Articles
Research Archive from 2006: A Hunter Medical Research Institute (HMRI) study has identified why asthmatics are more susceptible to the effects of the common cold which could lead to new treatments for acute asthma and health care savings.
Category: News & Articles
... and Jemma Mayall. The team discovered a protein, which they called Interferon epsilon (IFNe), and showed it plays an important role in ...
Category: Research
... Researchers have also successfully trialled an inhaled drug (called interferon-β) in asthmatics which may interfere with viruses in the ...
Category: News & Articles
... Professor Phil Hansbro and his team to define the roles and targeting interferon-epsilon as a new therapy for influenza in asthma and COPD. ...
