Category: Research
It has become apparent over the last decade that a class of molecules called long noncoding RNAs (lncRNA), which were originally thought to be ‘junk’ ... of cancer. Research Oncogenic upregulation of the long noncoding RNA MAFG-AS1 ...
Category: Researcher Profiles
... regulate immune responses known as T-cells, which produce signaling molecules (known as cytokines) that can dramatically increase ...
Category: Researcher Profiles
... a leading figure in investigation of the roles of microRNAs (small molecules that alter how genes are expressed) and Receptor-Interacting ...
Category: News & Articles
... discovery was made by investigating a special class of genes known as noncoding RNAs (ncRNA) found in the human genome (DNA). Led by Professor ... were twofold. On one hand, it acts like a sponge to absorb harmful molecules. On the other, it functions like a bridge that brings two ... to behave more like normal cells,” he added. With many times more noncoding genes than coding genes, the findings have unlocked new ...
Category: Researcher Profiles
... of phagocytes and esoinophil. Roles of small ‘non-coding’ RNA molecules in the differentiation of innate immune cells and in the ...
Category: Researcher Profiles
... oesophagitis and modulates them to find better treatments. Non-coding RNA molecules are involved in controlling how our genetic information is ... body cells. We were the first to prove that inhibiting some of these molecules can be inhibited in the lung to ameliorate allergy and ...
Category: News & Articles
... Professor Xu Dong Zhang was awarded $2.3m to explore long noncoding RNAs for cancer diagnosis and treatment. Compared to normal cells, cancer cells exploit a new class of molecules called nonprotein-coding RNAs for their malignancy. A better understanding of how these molecules influence cancer initiation, progression and treatment ...
Category: News & Articles
... cells. They named the molecule MILIP ( c-Myc -Inducible Long noncoding RNA Inactivating P53 ) and it was highly expressed in bowel cancer. ... is developing new drugs to target MILIP by working with a class of molecules that are non-coding RNAs. ” An RNA is a nucleic ...
Category: News & Articles
... maintain a healthy state. Dr Yuchen Feng $579,632 Exploiting long noncoding RNAs for lung cancer diagnosis and treatment Cancer cells exploit a newly discovered class of molecules for their growth and resistance to treatment. This research ... led by Dr Feng will develop a better understanding of how these molecules influence lung cancer initiation and treatment response. It ...