Category: Research
... tissue damage and inflammation, upregulating genes that aid bacterial survival while also potentially damaging the host. In particular, ... AL. This would have a profound effect on the management and survival of these patients. Research Analysis of luminal bacteria at the site of colorectal anastomoses and ...
Category: General
... of confounding; Sample size and power calculations Statistical analysis plans Advice on the treatment of missing data Use of ... discriminant analysis Poisson/negative binomial regression Survival analysis Exploratory factor analysis Dependent/correlated data ... with mixed models or GEEs) Meta-analysis/regression Competing risk survival analysis Predictive modelling with internal validation ...
Category: Researcher Profiles
... am also interested in applying different statistical methods for the analysis of various research questions, for example from clinical trials ... and practices, and public health. Proper statistical design and analysis is essential in all areas of medical and health research, to ... MPLUS, SAS, Stata, SPSS) Statistical analysis: longitudinal analysis, survival analysis, latent class analysis, three-step latent class ...
Category: Researcher Profiles
... different disease subgroups with different responses to treatment and survival outcome prediction. Carlos' expertise comes from a diverse ... the formulation of generalised models for data aggregation and meta-analysis, with mathematical guaranties of separability, to allow for ... Recent publications include application of these novel methods to the analysis of transcriptomics and genomics data in complex diseases such ...
Category: Researcher Profiles
... (AML) – the most common adult leukaemia, with a dismal 5year survival rate of just 24%; and breast cancer – a disease that kills ... cell biology can, and is, leading to better treatments and improved survival for cancer patients. The best advice I give to others is to ... Children’s Cancer Institute Australia and the Australian Proteome Analysis Facility, where she investigated the molecular mechanisms ...
Category: Researcher Profiles
... cancer-related deaths in Australian females. Two major challenges to survival are treatment resistance and metastases. To improve survival outcomes, improved therapies are urgently required. My ultimate ... Skills Biomarkers in cancer Microarrays Whole genome/methylome analysis Analysis of cell signaling 3D cell models Molecular approaches ...
Category: Research
... fifth leading cause of cancer death in Australia, with a five year survival rate of around 5%. (Source – Cancer Council Australia ). The treatment and survival of patients with pancreatic cancer has not changed for over ... to 40 patients simultaneously instead of individually, and where data analysis previously took three hours per person it now takes just 10 ...
Category: Research
... Helmet is an innovative tool which could have enormous impact for survival and disability rates for stroke victims. In NSW 16,000 acute ... Aims If acceptable feasibility of pre-hospital deployment/signal analysis along with the required high level of diagnostic accuracy can ... of subdural and subarachnoid haemorrhages and feed these into the analysis to train the algorithm. The clinical approach of the Newcastle ...
Category: Researcher Profiles
... processes are hijacked in cancer and this allows rapid growth and survival of cancer cells. I am specifically interested in: Finding ... after treatment (relapse), in order to combat cancer and increase survival of cancer patients. Biography Dr Bond is an Early Career ... Skills Single cell epigenetics DNA methylation and gene expression analysis Biomarkers of cancer prognosis Drug discovery including natural ...
Category: Research
... decreased capacity to transport oxygen. Unfortunately, the overall survival of a young person with SDS is only 35 years, and this is ... with no mechanistic understanding of transformation. Detailed analysis of SDS patient samples is desperately needed if we are to increase the survival and quality of life of patients. Importantly, the sophisticated ...