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  • News & Articles (37)
  • Research (17)
  • Researcher Profiles (16)
  • General (7)

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Malcolm Starkey
Category: Researcher Profiles
... the immune system. Studying immune responses to bacterial and viral infections both in early-life and adulthood to identify new ... strategies for common infections. Exploring how bacterial and viral infections exacerbate underlying chronic diseases, leading to more ... furthered the understanding of the deleterious effects of infection in early life and how these infections have long-term ...
Immunosenescence in chronic obstructive pulmonary disease leads to abnormal innate immune responses to human rhinovirus infection
Category: Research
... is punctuated by recurring chest infections, often triggered by viral infections such as human rhinovirus (HRV). These acute episodes ... as to why subjects with COPD are so susceptible to the effects of RV infection. We will determine if immunosenescence (an age dependent ... and does this affect the ability of these cells to respond to infection and repair. Research Immunosenescence in chronic obstructive ...
Effect of better asthma management in pregnancy on antiviral responses, atopy and airways inflammation in early childhood
Category: Research
... most common and severe virus-induced wheezy lower respiratory tract infection (LRTI) in the first year of life and recurrent LRTI are ...
Does healthy immune development during pregnancy set babies up for healthy respiratory viral responses
Category: General
... Program received a grant for his study into bronchiolitis, a severe viral infection that is the leading cause of babies under 12 months being ... development during pregnancy set babies up for healthy respiratory viral responses ...
Virus Infections Change the Bone Marrow: Effects on Immunity, Bone Development and Inflammatory Disease.
Category: Research
... long term changes throughout the body.  This study will determine if viral infections can cause changes to bone marrow and if these changes then alter anti-viral responses and the development of chronic inflammatory disease. ...
Understanding how lung infections in childhood promote the development of chronic lung diseases in later life
Category: Research
... changes in proteins in the lung following early-life bacterial and viral infections and determine which of these proteins may be targeted ...
Su-Ling Loo
Category: Researcher Profiles
... impact those in the community who are particularly susceptible to infection, particularly those with respiratory diseases or the elderly. ... in this model, as well as distinct induction of the innate anti-viral response. 229E had robust replication within 24 hours of infection ... OC43 a useful virus to study treatments that aim to restore an anti-viral response to SARS-CoV-2. In addition, the study of pathogenic ...
Does bronchoconstriction in asthma impair anti-viral immunity and promote airway inflammation
Category: Research
... also has other effects. During most asthma attacks airway narrowing, viral infection and inflammation of the airway occur simultaneously. Previous ... attacks. Research Does bronchoconstriction in asthma impair anti-viral immunity and promote airway inflammation ...
Peter Wark
Category: Researcher Profiles
What are your research interests? Viral respiratory tract infections and factors that make the patient ... in airway secretions and developing an in-vitro cell culture model of infection. The role of the airway epithelium in innate immunity and ... at HMRI.  Professor Wark was among the first to demonstrate that viral infection was the most common trigger for acute severe asthma in ...
Alan Hsu
Category: Researcher Profiles
... Disease (COPD) : People with asthma or COPD are highly vulnerable to viral infections, leading to severe symptoms with increased risk of ... human health.  Dr Hsu is investigating the mechanisms of influenza infection and potential immune abnormalities that are present in those ... Putra Malaysia for a special seminar on his current work on viral infections and immunity in 2015.  Dr Hsu has been successful in ...
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