What are your research interests?
- Urinary incontinence and bladder disorders in children
- Medical and social morbidity resulting from complex, surgical diseases in children
- Developing high quality evidence in surgical research
Why did you get into research?
During my surgical training I noticed a high prevalence of bladder problems in children. Coupled with a limited understanding, this common problem has a significant impact on the psychosocial wellbeing of the child as well as the family.
As a paediatric surgeon, I am aware of the enormous difficulties faced by the patients, families and the health care teams dealing with complex surgical diseases in children. I decided to dedicate myself to research into urinary incontinence and complex surgical diseases in children.
What is your dream?
Through improved understanding and effective treatment strategies of bladder and complex surgical diseases in children, my dream is to enable these children and their families to lead a normal life.
Dr Deshpande is a Fellow of the Royal Australasian College of Surgeons and works as a paediatric urological surgeon at John Hunter Children’s Hospital, Newcastle. He is also associated with the School of Medicine of Public Health, University of Newcastle, and has varied research interests closely related to his area of clinical expertise. These include complex surgical diseases in children and kidney disease in children. He has been awarded a PhD in the study of bladder disorders and urinary incontinence in children by the University of Sydney.
His current research is structured around identifying the long-term impact of kidney diseases and complex surgical diseases on lung function of growing children. He is also involved in developing the highest quality of evidence for surgical treatments under the backing of the Cochrane collaboration. He is developing research protocols for understanding perspectives of parents of children with complex surgical diseases in the Hunter in order to improve the treatment and support strategies.
He is a member of the ACI Collaborative Group of Urinary Incontinence in Children. ACI is the NSW Agency for Clinical Innovation and this working group is entrusted with evolving strategies for improved care of children suffering from urinary incontinence. Dr Deshpande has over 30 publications in peer reviewed journals and has supervised medical students doing research projects.
Specialised/ Technical Skills
- Paediatric Urological Surgery
- Systematic reviews in Medicine
- Urodynamic testing in Children including Ambulatory Urodynamics
Urinary leakage in the daytime, feeling of urgency to urinate and frequent urination are common and often incapacitating problems in school-aged children. If affects 5-10% of healthy, otherwise normal children and significantly disrupts their day-to-day life and learning.(6,7) This has consequences for mental health and healthy development.
Kidney stones affect approximately 9% of the population, with rates increasing globally. Whilst the surgical techniques used to remove obstructive stones have improved, few if any advances have been made to prevent stone recurrence. Stones are a significant risk factor for the development of chronic kidney disease, which currently affects 2 million Australians.
The countess II FL is the major component of this equipment and is the core module that enables highly accurate, reproducible and high throughput cell counting. The Countess II reuse slide enables the same slide to be used for an infinite number of experiments and reduces consumable costs associated with individual slides. However, this equipment allows options for users who need individual slides at their own expense. The two EVOS LED Cubes are removable components that allow quantification of fluorescent cells. We have chosen green fluorescent protein and red fluorescent protein as these are the major fluorophores used. However, these can be switched out for other detectors in the future, making it future proof and adaptable to future research needs.
Acute kidney injury is increasing in incidence globally and there is a strong association between acute kidney injury and the development of chronic kidney disease.