Project Stage 1 - Complete
With the support from the McGuigan family we have completed the pilot study of 100 ovarian cancer tumor samples from the Hunter region. We found that high levels of the protein ERCC1 measured AFTER cisplatin chemotherapy accurately predict long-term response to treatment.
Stage 2 (this project)
To build on Stage 1, we have requested an additional 400 ovarian cancer tumour samples from the Australian Ovarian Cancer Study (AOCS). We will test the levels of ERCC1 protein in the 400 samples and run statistical analysis to confirm our findings from Stage 1.
If these results are confirmed in Stage 2 we will proceed to develop a diagnostic test to be used to make more effective patient treatment decisions.