Our aim is to determine which of two dietary approaches is more effective in reducing migraine frequency, severity and duration. In a cross-over trial, we will evaluate the feasibility, acceptability and efficacy of a ketogenic diet (high in fat, low in total carbohydrate, and moderate amounts of protein) monitored as part of medical nutrition therapy, compared to an ‘anti-headache diet’ we have developed based on our review of the research evidence (e.g. drinking an extra 1.5 litres of water daily, monitoring caffeine intake, eating consistently by having regular daily meal/snack times, avoiding fasting and avoiding alcohol).
Outcomes and significance
Developing a feasible and effective dietary management approach for those who regularly suffer from migraine has the potential to improve their quality of life and reduce the number of days of leave needed due to migraine.