Lucy’s research investigates the role of various molecular factors responsible for heart remodelling using in vitro and in vivo techniques, including echocardiography and pressure-volume loop analysis. This award will allow Lucy to conduct pilot studies investigating a particular molecular target of interest (called Fibulin-3), and will allow her to visit an international expert in Canada, to acquire essential skills in echocardiography and PV loop analysis.
Following a cardiovascular event (e.g. heart attack) the heart undergoes significant physical changes, including an increase in scar tissue, changes in morphology and decreased functional capacity (heart remodelling).