The role of microbiome development in the early origins of asthma in a high risk population

Children born to mothers with asthma are three times more likely to develop asthma themselves than those with asthmatic fathers, which suggests that a risk factor extends beyond genetics. There is emerging evidence that bacteria in the infant’s gut can impact immune function and contribute to the types of immune responses that are seen in asthma.

In this study, Dr Collison will investigate if there are differences in the types of bacteria and the timing of colonisation through the first year of life. It will allow him to examine which colonisation patterns are associated with a risk of developing asthma and may assist in developing prevention strategies.

Researchers

Dr Adam Collison, Professor Joerg Mattes

Research Area

Viruses, Infections / Immunity, Vaccines & Asthma

Project type

Project Grant

Year of funding

2016

Funded by

Hunter Children's Research Foundation

Our Role & Impact

The role of microbiome development in the early origins of asthma in a high risk population