An online intervention to improve child dietary intake in childcare.

Internationally, 41 million children aged 0-5 years were overweight or obese in 2016(1). Poor nutrition is one of the most important risk factors for the development of obesity(2). As early childhood is a formative time for developing healthy eating behaviours, population health strategies that support children to eat better are of upmost importance(3).

Understanding how cohabiting bacteria in urine influence treatment of urinary infections and urinary leakage in children: a pilot study

Urinary leakage in the daytime, feeling of urgency to urinate and frequent urination are common and often incapacitating problems in school-aged children. If affects 5-10% of healthy, otherwise normal children and significantly disrupts their day-to-day life and learning.(6,7)  This has consequences for mental health and healthy development.

Understanding the link between immune cell function and lung function in the development of asthma in early life

Asthma affects one in eight children in Australia and is the leading cause of hospitalisations and emergency visits, with an estimated annual health care cost of more than 24 billion Australian dollars in 2015. Asthma is the most common medical complication in pregnancy and is strongly associated with the development of childhood asthma. ntion strategy for asthma.

A randomised controlled trial to assess the impact of a uniform intervention on girl’s physical activity at school.

Children’s participation in at least 60 minutes of moderate-to-vigorous physical activity (MVPA) per day is essential for their healthy growth and development[ and the prevention of future chronic disease. Despite this, international research indicates that many school-aged children, in particularly girls, are not sufficiently active. It is estimated that girls are between 17-19% less active than boys with differences beginning from as young as 8 years. Improving physical activity during childhood, particularly among girls, has been identified as a public health priority.

Re-purposing PARP inhibitors to treat childhood leukaemias

Cancer is the most common cause of childhood disease-related deaths, with leukaemia the most common childhood cancer in Australia. The two most common forms of leukaemia in children are acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML). Whilst remission is achievable in over 95% of ALL cases, 1/3 of patients will relapse within 5 to 10 years, and these children will not be long-term survivors. AML accounts for 20% of all childhood leukaemias, and the outlook for children diagnosed with AML is much worse, with only approximately half of children surviving for 5 years post-diagnosis.

Development and pilot study of an evidence-based internet intervention to improve symptoms, functioning and health-related quality of life in children with functional abdominal pain

Cognitive-Behaviour Therapy, or CBT, is one of the few effective therapies for children with functional abdominal pain. But CBT sessions can be costly and difficult to access, particularly as multiple sessions are required.

The role of microbiome development in the early origins of asthma in a high risk population

Children born to mothers with asthma are three times more likely to develop asthma themselves than those with asthmatic fathers, which suggests that a risk factor extends beyond genetics. There is emerging evidence that bacteria in the infant’s gut can impact immune function and contribute to the types of immune responses that are seen in asthma.