At any time, there are hundreds of thousands of clinical trials and research projects taking place across the world in a wide range of disease and health areas including stroke, cancer, asthma and more.

Those who participate in clinical trials and other studies are often the first to access and benefit from new and emerging treatments across a range of areas.

You can learn more about how to access the latest medical research through a research project or clinical trial below.

 

FIND OUT ABOUT
RESEARCH PROJECTS

There are a number of research projects that allow eligible people to access emerging medical research and treatments in a range of areas.

Those involved also have the satisfaction of one helping someone else with an illness, providing important scientific information that will be used to develop new disease treatments and improve already existing ones.

 

Research Register

The Research Register recruits a central database of people who are interested in contributing to medical research. The Register helps researchers access to the type of people they require in their efforts to improve the health of the community.

 

Hunter Stroke Research Volunteer Register

The Hunter Stroke Research Volunteer Register recruits a database of people with stroke, living in the Hunter region, who are willing to be contacted to participate in research at a later date. The Register will be a centralised process for contacting people with stroke who would like to take part in research.

 

Research Projects Currently Recruiting

Carer's falls concern for older persons

Are you a carer? Researchers are seeking volunteers to understand about the carers’ concern for older people at risk of falling at home. 

Click here to find out more

Over the mealtime battles? Want your family to eat healthier?
Researchers are seeking families with kids 4-11 years to participate in a new online nutrition program to improve eating habits and lifestyle.

Click here to find out more
Are you interested in a new way to treat your asthma or COPD?
Researchers are seeking non-smoking volunteers to test the effectiveness of a drug on improving symptoms of asthma and COPD.

Click here to find out more
 AUSPICE: Australian Study for the Prevention through Immunisation of Cardiovascular Events
Participate in a national study to test whether a one-off vaccine can reduce the risk of heart attack and stroke.

Click here to find out more
Immunogenetic Profiles in Multiple Sclerosis
Research Areas: Multiple Sclerosis
Investigators: A/Prof Jeannette Lechner-Scott, A/Prof Rodney Lea, Prof. Rodney Scott, Dr. Vicki Maltby, Ms Kira Groen
Location: HMRI Building and John Hunter Hospital

Click here to find out more
Fast MRSI Techniques in MS
You are invited to take part in a research study, as a healthy control participant, in a research study aimed at gaining a better understanding Multiple Sclerosis (MS).

Click here to find out more
PEAnut Anaphylaxis Predictors (PEAAP Study)

Peanut allergy is often diagnosed when hives, swelling, difficulty breathing or collapse (anaphylaxis) occur shortly after eating food containing peanuts. An allergy to peanut is confirmed either by a blood test or a Skin Prick Test (SPT). These tests however, are not always able to identify peanut allergy with certainty. Because there isn’t a definitive blood or skin test for diagnosing peanut allergy, diagnosing peanut allergy often still requires the patient to eat peanut to be certain of an allergy to peanuts.

This study aims to determine if a new blood test and breathing test are able to predict if a severe allergic reaction will occur during a peanut food challenge. This may mean that in future some children can have a blood test instead of having to eat peanut in a food challenge.

This study is suitable for Children and adolescents between the ages of 6-17 years with a suspected peanut allergy.

The study will involve your child:

  • Answering a 5 minute questionnaire (you can do this on behalf of your child);
  • Having a Skin prick test to peanut,
  • Performing 2 different breathing tests (one to measure lung flows/volumes and a second to measure the concentration of a particular gas [Nitric oxide] in the breath),
  • Giving a blood sample to measure antibodies to peanut and other biomarkers,
  • Undergoing a peanut food challenge, where your child will be given increasing amounts of peanut and closely monitored any for signs of allergic reaction,
  • Repeating one of the breathing tests (FeNO) after each dose of peanut and at the completion of the food challenge.

If you are interested in this study please contact: 0427 326 890 or email elizabeth.percival@hnehealth.nsw.gov.au


Improving Asthma in Childhood through Diet

Chief Investigator: Professor Lisa Wood

Project Title: Improving Asthma in Childhood through Diet (ImpACt)

Study Location: HMRI Building

Purpose of the Study: Asthma is the most common chronic childhood disease, affecting one in seven children. Many children have asthma flare-ups, which often results in several sick days requiring increased use of medications, such as ventolin, and may lead to an emergency room visit or even a hospital admission. We have conducted studies in adults, which indicate that certain dietary changes can reduce the risk of an asthma flare-up. However, we do not know whether this is true in children. This study will examine whether the frequency of asthma flare-ups in children can be reduced, by making specific changes to the diet. We hope to gain insight into how diet may be useful for managing children with asthma.

Participant Tasks: Participants will complete questionnaires, undergo breathing tests, and have a blood sample collected on three occasions over the 6-month trial period. During the 6 month trial, participants will have regular contact with a dietitian who will monitor their assigned diet. Participants will be provided with a weekly food hamper containing the food items we wish the child to eat during the study. We will also provide an additional hamper for other family members to enjoy, so that we can be sure that the participant eats the required food.

Participant Criteria: Participants must be 3 to 11 years of age, have a doctor’s diagnosis of asthma and have been unwell due to their asthma in the past year. Participants must be willing to alter their dietary intake for the study period.

For more information about this study, please contact the Megan Jensen

Call: (02) 4042 0115

Call or SMS: 0427 172 107

Email: megan.jensen@newcastle.edu.au

Asthma Management During Pregnancy

Research Areas: Pregnancy, asthma, women’s health, paediatrics

Investigators: Dr Vanessa Murphy, Prof Peter Gibson

Location: HMRI Building or John Hunter Hospital.

Additional sites: This is a multi-centre trial and is being conducted at the Royal Hospital for Women in Randwick, the Nepean Hospital, the Royal Brisbane and Women’s Hospital, and the Royal North Shore Hospital.

Project Title: The Breathing for Life Trial (BLT): a randomised trial of fractional exhaled nitric oxide (FENO)-based management of asthma during pregnancy and its impact on perinatal outcomes and infant and childhood respiratory health.

Purpose of the Study: Asthma affects more than 12% of pregnant women in Australia, and these women have an increased risk of poor pregnancy outcomes such as preterm birth and hospitalisation of the newborn. Better management of asthma in pregnancy may significantly reduce the impact of these major adverse outcomes on the offspring. The Breathing for Life Trial will test the hypothesis that using a simple breath test to measure lung inflammation (FENO) to adjust asthma medication in pregnancy will be superior to usual care in improving maternal and perinatal health, and have long term benefits to the offspring. We wish to investigate the response to this management approach in both women who smoke and women who do not smoke.

Participant Tasks: Participants will be randomly allocated to the control group (usual care) or the intervention group (FENO-based management). Women in the control group will have one visit at HMRI or the JHH for some breathing tests and to be provided with asthma self-management education. Management of their asthma will be with their usual primary care provider. Women in the FENO group will have visits every 3-6 weeks during pregnancy for breathing tests, asthma self-management education and every 2 visits will have their medication adjusted based on the results of their FENO breathing test and the asthma control questionnaire. Participants in both groups will be telephoned after delivery to obtain information about asthma flare-ups during pregnancy, and will have the option to have their infant followed up in Respiratory and Development studies.

Participant Criteria: Doctor diagnosed asthma, 18 years of age or older, 12-22 weeks gestation, smokers and non-smokers.

For more information about this study, please contact Dr Megan Jensen.

Phone: (02) 4042 0130

Email: breathingforlifetrial@gmail.com

 

FIND OUT ABOUT
CLINICAL TRIALS

At any time, there are thousands of clinical trials taking place across the world in a wide range of disease and health areas. Those who participate in clinical trials and other studies are often the first to access and benefit from new and emerging treatments across a range of areas.

The Australian New Zealand Clinical Trials Registry is an online registry that allows you to search for clinical trials currently available in Australia and New Zealand.

You can search the ANZCTR by location and disease or health area.

The search function on ANZCTR allows you to conduct either a basic search or an advanced search of clinical trials available on the ANZCTR database. Once you find a relevant trial, you will be able to contact the health care or research professional listed as the 'public contact' on the trial record for more information.

If you wish to search of clinical trials for a local trial, try putting the location and health or disease area in the search field. For example, Asthma, Newcastle.

To find out more information about how to be part of clinical trial, the first important step is to find out more information about clinical trials in general and what is involved in being part of a clinical trial.

There is a lot of information available online about the clinical trial process, the ethics and regulation of clinical trials and why a person would want to be a part of a trial in Australia.

A good place to start is the Australian Government’s National Health and Medical Research Council.

You can find out a great deal of information about clinical trials by visiting the site below.

Who Can Help?

You can also talk to any health professional involved in your care about upcoming clinical trials. This includes general practitioners (GPs), specialists, or nursing or allied health professionals. Your health care team may be able to provide general information about clinical trials and could have information on clinical trials that are relevant to you.

Support groups or consumer health organisations with an interest in a particular disease or condition that you are interested in may also have information on trials, or be able to provide contact information for other patients who have been involved in trials.

FOR RESEARCHERS -
RESEARCH PROJECT SUPPORT

HMRI offers a range of services to support HMRI affiliated researchers throughout each stage their research project.

These services include: