At any time, there are hundreds of thousands of clinical trials and research projects taking place across the world in a wide range of disease and health areas including stroke, cancer, asthma and more.

Those who participate in clinical trials and other studies are often the first to access and benefit from new and emerging treatments across a range of areas.

You can learn more about how to access the latest medical research through a research project or clinical trial below.



There are a number of research projects that allow eligible people to access emerging medical research and treatments in a range of areas.

Those involved also have the satisfaction of one helping someone else with an illness, providing important scientific information that will be used to develop new disease treatments and improve already existing ones.


Research Register

The Research Register recruits a central database of people who are interested in contributing to medical research. The Register helps researchers access to the type of people they require in their efforts to improve the health of the community.

Learn more about the research register


Stroke Research Register - Hunter

The Stroke Research Register - Hunter recruits a database of people with stroke, living in the Hunter region, who are willing to be contacted to participate in research at a later date. The Register will be a centralised process for contacting people with stroke who would like to take part in research.

Learn more about the Stroke Research Register - Hunter


Research Projects Currently Recruiting

Help Co-Design an Exercise Program for Stroke Survivors
Researchers are looking for stroke survivors who would like to help to co-design an exercise program that will be delivered over the internet. The program’s aim is to support people who have had a stroke to get more active and reduce their risk of having another stroke.

Click here to find out more 
Have you had a stroke in the last 14 weeks? Join our arm function study 

Researchers are seeking volunteers for a study looking at rehabilitation of arm function after stroke.

The study would involve assessments of arm and hand function, before and after a 6 week period, during which training may be given to improve arm and hand function. There will also be a follow-up assessment after 6 months.

Click here to find out more

Understanding menstrual migraines - seeking women with and without migraines
Researchers are seeking premenopausal women aged 18 years and over to participate in a study examining links between blood flow in the brain and menstrual migraine.

Click here to find out more
Stroke fatigue - wakefulness drug
Researchers are looking for people with debilitating fatigue after stroke to test a wakefulness medication called modafinil.

Click here to find out more
Have you had a stroke between 3 months and 10 years ago?
Researchers are seeking volunteers for a study looking at the amount of short activity breaks needed to improve blood pressure in stroke survivors and reduce their risk of having another stroke.

Click here to find out more
Can you read between the lines in social situations?
Researchers are seeking volunteers, 30-65 years, to help validate a new measure of social skills.

Click here to find out more
What about new dads? - The WAND Study
Researchers are seeking fathers of infants to complete a 15-minute online survey investigating the relationships between postnatal thoughts and parental wellbeing.  

Click here to find out more
Healthy volunteers needed to help understand cognitive decline
The “Cognitive Ability Pathways” study examines whether people who have experienced a minor neurological event have greater risk of cognitive decline than other people their age. Researchers are seeking healthy participants with no or low cardiovascular risk factors to act as control participants in this research.

Click here to find out more
Would you like a trial run at being a new parent?
Researchers are seeking new parents of infants aged 1 to 13 months to trial a new game-based learning experience.

Click here to find out more
Healthy eating and weight gain in pregnancy.

Click here to find out more
Exercise Training for Asthma Study
Do you have asthma? Researchers are seeking volunteers to examine how exercise training may improve asthma.

Click here to find out more
Over the mealtime battles? Want your family to eat healthier?
Researchers are seeking families with kids 4-11 years to participate in a new online nutrition program to improve eating habits and lifestyle.

Click here to find out more
Are you interested in a new way to treat your asthma or COPD?
Researchers are seeking non-smoking volunteers to test the effectiveness of a drug on improving symptoms of asthma and COPD.

Click here to find out more
Immunogenetic Profiles in Multiple Sclerosis
Research Areas: Multiple Sclerosis
Investigators: A/Prof Jeannette Lechner-Scott, A/Prof Rodney Lea, Prof. Rodney Scott, Dr. Vicki Maltby, Ms Kira Groen
Location: HMRI Building and John Hunter Hospital

Click here to find out more
PEAnut Anaphylaxis Predictors (PEAAP Study)

Peanut allergy is often diagnosed when hives, swelling, difficulty breathing or collapse (anaphylaxis) occur shortly after eating food containing peanuts. An allergy to peanut is confirmed either by a blood test or a Skin Prick Test (SPT). These tests however, are not always able to identify peanut allergy with certainty. Because there isn’t a definitive blood or skin test for diagnosing peanut allergy, diagnosing peanut allergy often still requires the patient to eat peanut to be certain of an allergy to peanuts.

This study aims to determine if a new blood test and breathing test are able to predict if a severe allergic reaction will occur during a peanut food challenge. This may mean that in future some children can have a blood test instead of having to eat peanut in a food challenge.

This study is suitable for Children and adolescents between the ages of 6-17 years with a suspected peanut allergy.

The study will involve your child:

  • Answering a 5 minute questionnaire (you can do this on behalf of your child);
  • Having a Skin prick test to peanut,
  • Performing 2 different breathing tests (one to measure lung flows/volumes and a second to measure the concentration of a particular gas [Nitric oxide] in the breath),
  • Giving a blood sample to measure antibodies to peanut and other biomarkers,
  • Undergoing a peanut food challenge, where your child will be given increasing amounts of peanut and closely monitored any for signs of allergic reaction,
  • Repeating one of the breathing tests (FeNO) after each dose of peanut and at the completion of the food challenge.

If you are interested in this study please contact: 0427 326 890 or email

Asthma Management During Pregnancy

Research Areas: Pregnancy, asthma, women’s health, paediatrics

Investigators: Dr Vanessa Murphy, Prof Peter Gibson

Location: HMRI Building or John Hunter Hospital.

Additional sites: This is a multi-centre trial and is being conducted at the Royal Hospital for Women in Randwick, the Nepean Hospital, the Royal Brisbane and Women’s Hospital, and the Royal North Shore Hospital.

Project Title: The Breathing for Life Trial (BLT): a randomised trial of fractional exhaled nitric oxide (FENO)-based management of asthma during pregnancy and its impact on perinatal outcomes and infant and childhood respiratory health.

Purpose of the Study: Asthma affects more than 12% of pregnant women in Australia, and these women have an increased risk of poor pregnancy outcomes such as preterm birth and hospitalisation of the newborn. Better management of asthma in pregnancy may significantly reduce the impact of these major adverse outcomes on the offspring. The Breathing for Life Trial will test the hypothesis that using a simple breath test to measure lung inflammation (FENO) to adjust asthma medication in pregnancy will be superior to usual care in improving maternal and perinatal health, and have long term benefits to the offspring. We wish to investigate the response to this management approach in both women who smoke and women who do not smoke.

Participant Tasks: Participants will be randomly allocated to the control group (usual care) or the intervention group (FENO-based management). Women in the control group will have one visit at HMRI or the JHH for some breathing tests and to be provided with asthma self-management education. Management of their asthma will be with their usual primary care provider. Women in the FENO group will have visits every 3-6 weeks during pregnancy for breathing tests, asthma self-management education and every 2 visits will have their medication adjusted based on the results of their FENO breathing test and the asthma control questionnaire. Participants in both groups will be telephoned after delivery to obtain information about asthma flare-ups during pregnancy, and will have the option to have their infant followed up in Respiratory and Development studies.

Participant Criteria: Doctor diagnosed asthma, 18 years of age or older, 12-22 weeks gestation, smokers and non-smokers.

For more information about this study, please contact Cat Delahunty.

Phone: (02) 4042 0130




At any time, there are thousands of clinical trials taking place across the world in a wide range of disease and health areas. Those who participate in clinical trials and other studies are often the first to access and benefit from new and emerging treatments across a range of areas.

The Australian New Zealand Clinical Trials Registry is an online registry that allows you to search for clinical trials currently available in Australia and New Zealand.

You can search the ANZCTR by location and disease or health area.

The search function on ANZCTR allows you to conduct either a basic search or an advanced search of clinical trials available on the ANZCTR database. Once you find a relevant trial, you will be able to contact the health care or research professional listed as the 'public contact' on the trial record for more information.

If you wish to search of clinical trials for a local trial, try putting the location and health or disease area in the search field. For example, Asthma, Newcastle.

To find out more information about how to be part of clinical trial, the first important step is to find out more information about clinical trials in general and what is involved in being part of a clinical trial.

There is a lot of information available online about the clinical trial process, the ethics and regulation of clinical trials and why a person would want to be a part of a trial in Australia.

A good place to start is the Australian Government’s National Health and Medical Research Council.

You can find out a great deal of information about clinical trials by visiting the site below.

Who Can Help?

You can also talk to any health professional involved in your care about upcoming clinical trials. This includes general practitioners (GPs), specialists, or nursing or allied health professionals. Your health care team may be able to provide general information about clinical trials and could have information on clinical trials that are relevant to you.

Support groups or consumer health organisations with an interest in a particular disease or condition that you are interested in may also have information on trials, or be able to provide contact information for other patients who have been involved in trials.


HMRI offers a range of services to support HMRI affiliated researchers throughout each stage their research project.

These services include: