At any time, there are hundreds of thousands of clinical trials and research projects taking place across the world in a wide range of disease and health areas including stroke, cancer, asthma and more.

Those who participate in clinical trials and other studies are often the first to access and benefit from new and emerging treatments across a range of areas, and have the satisfaction of one helping someone else with an illness, providing important scientific information that will be used to develop or improve disease treatments.

There are a number of research projects at HMRI that allow eligible people to access emerging medical research and treatments in a range of areas. Learn more about these projects and how you can become involved below.


Research Register

The Research Register recruits a central database of people who are interested in contributing to medical research. The Register helps researchers access to the type of people they require in their efforts to improve the health of the community.

Learn more about the research register


Stroke Research Register - Hunter

The Stroke Research Register - Hunter recruits a database of people with stroke, living in the Hunter region, who are willing to be contacted to participate in research at a later date. The Register will be a centralised process for contacting people with stroke who would like to take part in the research.

Learn more about the Stroke Research Register - Hunter


Research Projects Currently Recruiting

Teacher Food and Nutrition Questionnaire

Be part of a new research study, that looks at the important contribution of food and nutrition to health and wellbeing.

Health and wellbeing are more important than ever, and the contribution of dietary and culinary factors is an emerging area of interest.

Teachers are key individuals within the school environment and it's important to identify ways to support their health and wellbeing.

Our research aims to test a screening tool to assess the contribution of food and nutrition factors to teacher health and wellbeing.  

Click here to find out more

Dementia - Alzheimer's Lecanemab Clinical Trial 

Here at HMRI, Professor Michael Breakspear is heading the regional arm of the Australian Dementia Network (ADNeT), which is a national multi-site project to pre-screen potential participants for local clinical trials into Dementia.

One of the current local trials is the AHEAD trial which is testing the drug lecanemab’s (BAN2401) ability to prevent cognitive deterioration before noticeable signs of Alzheimer’s disease have commenced.

Watch this brief NBN news clip where Michael explains our study here at HMRI.

If you would like to become a volunteer please register your interest on the ADNeT volunteer portal.

Volunteers needed for research into hearing loss and brain health in later life

We are looking for both people with acquired hearing loss that are eligible for treatment with cochlear implant devices, as well as healthy adults who do not have hearing loss to participate.

Left untreated, acquired hearing loss is known to be a significant risk factor for developing dementia in later life.

Our researchers are using MRI brain imaging to measure changes in brain function and structure after cochlear implant surgery. The aim of this project is to establish how the treatment of acquired hearing loss reduces the risk and severity of dementia onset, and to promote healthy ageing through early interventions.

Click here to find out more

iACT Study for carers of advanced cancer

Are you a carer for someone with advanced cancer? 

Researchers are currently looking at ways they can provide support to carers of people with advanced cancer. 

Click here to find out more

NF1 Project Consortium
We invite adults with neurofibromatosis type 1 (NF1) to participate in the international NF1 cutaneous neurofibroma consortium project which aims to improve our understanding of how genetics affects the number of skin neurofibromas a person with NF1 may develop.

Click here to find out more

Have you had a stroke?  You can help!

Researchers are looking for people who have had a stroke, to help test a prototype of computer character (like a virtual assistant that is sometimes seen on websites).   The idea is that the computer character will be trained to deliver a program that can help people with their recovery, through talk sessions about what’s important to them. For now, they’re looking for people to interact with the computer character and tell us what they like and don’t like about it.

Click here to find out more

Dietary Patterns and Cardiovascular Disease Risk

Dietary patterns, rich in plant-derived foods have gained popularity in Australia and worldwide due to societal trends, ethical and environmental sustainability concerns and perceived healthiness.
Our researchers are currently examining the relationship between the health status of Australian adults and the types of plant-based dietary patterns followed.

Click here to find out more
Measuring your intake - can a survey accurately tell us what stroke survivors eat?

To make programs that support stroke survivors to eat well, we need to know what their current diet looks like.

We would like to find out whether the tools we usually use to measure your diet work well for stroke survivors

Click here to find out more

Healthy volunteers needed for research into mental illness

We are inviting people between 16-50 years of age who do not have a serious mental health condition, who can serve as baseline participants for this study

Click here to find out more
Survivors of stroke who experience severe fatigue - we want to talk to you to understand this better

Fatigue after stroke is a major problem and we don’t know what the best treatments are.  
Researchers are interviewing people who have had a stroke and/or their carer (friend or family) to hear about the lived experience of post-stroke fatigue. What has or has not helped? 

Click here to find out more

 Anti-viral Dietary Supplement for Immune Health: LIFE Trial Are you aged 50 years and over?

Researchers are looking for volunteers to participate in a trial testing a dietary supplement which may improve immune function and protect against virus infection.

Click here to find out more
Help design the iREBOUND online program - for eating well and moving after stroke

Researchers are looking for stroke survivors and people who care for them to help to design an online program for secondary stroke prevention. You could help to make sure that the online iREBOUND program meets the needs of a diverse range of people with stroke who want to eat well and move more. 

Learn more here

 Digestive Health and Wellbeing Survey

We would like to invite you to complete the Digestive Health & Wellbeing Survey (DHWS) and the Structured Assessment of Gastrointestinal Symptoms Scale (SAGIS). These surveys contribute to digestive health research by providing information that will allow us to better characterise gastrointestinal problems.
They will ask for information about your gut symptoms, anxiety and depression, sleep, smoking and alcohol intake. This helps us understand why some people develop conditions and others do not. We would like people with and without gut problems to participate

Click here to learn more about this survey and to participate
 ESTEEM Stroke Workshops

Have you had a stroke?  Are you a carer for someone who has had a stroke? You can help!

Researchers are inviting people who have had a stroke, or present or previous carers for someone who has had a stroke, to help design a long-term recovery group for stroke survivors. The aim of the group is to incorporate exercise, socialising and art-based thinking activities to improve recovery and quality of life for people living with stroke.

Click here to find out more and to register

Stroke Survivors – reduce your risk of having another stroke using video calls
Exercise and a good diet after stroke will reduce the risk of having another stroke in the future. 

Researchers are testing programs for people who have had a stroke. The aim is to increase your physical activity and improve your diet. Best of all, these programs are delivered over the internet so there’s no need to leave your home to participate.

Click here to find out more
Understanding Breathlessness in Asthma
Researchers are inviting people with asthma to participate in a study aiming to understand breathlessness

Click here to find out more
How Diet affects Asthma Medications
Help us find the right type of asthma medication for you. Researchers are looking for volunteers with asthma to participate in a study looking at how diet affects asthma medications.

Click here to find out more
Treatment of Acute Cough in Upper Respiratory Tract Infection (TAC)

We are conducting a research study into an early intervention for cough following an upper respiratory tract infection, also known as the 'common cold'

Click here to find out more
Have you had a TIA or 'mini-stroke'? You can help!

Researchers are inviting people who have had a TIA or ‘mini-stroke’ to come to four (4) appointments at HMRI across a 6-month period. They would take measurements from you including blood tests and a small hair sample to understand more about stroke prevention.

Click here to find out more
Have you had a stroke in the last 14 weeks? Join our arm function study 

Researchers are seeking volunteers for a study looking at rehabilitation of arm function after stroke.

The study would involve assessments of arm and hand function, before and after a 6 week period, during which training may be given to improve arm and hand function. There will also be a follow-up assessment after 6 months.

Click here to find out more

Mitigating Menstrual Migranes

Researchers are seeking premenopausal women aged 18 years and over to participate in a clinical trial that is investigating whether a nutritional supplement (resveratrol) can prevent menstrual migraines.

Click here to find out more
Stroke fatigue - wakefulness drug

Researchers are looking for people with debilitating fatigue after stroke to test a wakefulness medication called modafinil.

Click here to find out more
What about new dads? - The WAND Study
Researchers are seeking fathers of infants to complete a 15-minute online survey investigating the relationships between postnatal thoughts and parental wellbeing.  

Click here to find out more
Would you like a trial run at being a new parent?
Researchers are seeking new parents of infants aged 1 to 13 months to trial a new game-based learning experience.

Click here to find out more
Healthy eating and weight gain in pregnancy.

Click here to find out more
Asthma Management During Pregnancy

The Breathing for Life Trial Nutrition Study: A study of maternal and infant diet and nutritional health and its relation to respiratory health.

Click here to find out more


Knowledge truly is power and the musculoskeletal health team wants to empower people in pain with as much knowledge as possible to help you make better decisions about your health and the care you receive.  That’s why they’ve just launched the HeLP (Healthy lifestyle for back pain) e-course.  A FREE, ten-day education series that gets delivered straight to your inbox daily packed with science based information, tips and resources to help you manage your pain. Tackling a health problem as big and as complex as chronic pain is no small feat, however a team of researchers from HMRI and the University of Newcastle are dedicated to easing the burden that pain sufferers experience and changing the way care is delivered through innovation and collaboration.

Click here to find out more and to register



At any time, there are thousands of clinical trials taking place across the world in a wide range of disease and health areas. Those who participate in clinical trials and other studies are often the first to access and benefit from new and emerging treatments across a range of areas.

The Australian New Zealand Clinical Trials Registry is an online registry that allows you to search for clinical trials currently available in Australia and New Zealand.

You can search the ANZCTR by location and disease or health area.

The search function on ANZCTR allows you to conduct either a basic search or an advanced search of clinical trials available on the ANZCTR database. Once you find a relevant trial, you will be able to contact the health care or research professional listed as the 'public contact' on the trial record for more information.

If you wish to search of clinical trials for a local trial, try putting the location and health or disease area in the search field. For example, Asthma, Newcastle.

To find out more information about how to be part of clinical trial, the first important step is to find out more information about clinical trials in general and what is involved in being part of a clinical trial.

There is a lot of information available online about the clinical trial process, the ethics and regulation of clinical trials and why a person would want to be a part of a trial in Australia.

A good place to start is the Australian Government’s National Health and Medical Research Council.

You can find out a great deal of information about clinical trials by visiting the site below.

Who Can Help?

You can also talk to any health professional involved in your care about upcoming clinical trials. This includes general practitioners (GPs), specialists, or nursing or allied health professionals. Your health care team may be able to provide general information about clinical trials and could have information on clinical trials that are relevant to you.

Support groups or consumer health organisations with an interest in a particular disease or condition that you are interested in may also have information on trials, or be able to provide contact information for other patients who have been involved in trials.


HMRI offers a range of services to support HMRI affiliated researchers throughout each stage their research project.

These services include: