Cardiovascular Health

Phase I of this study will investigate feasibility and efficacy of a self-help, gender-tailored weight loss program for male workers with or without the provision of additional program components targeting stress and mental health  (SHED-IT only vs. SHED-IT plus SHED-IT: Recharge).

Migraines are headaches so severe that the World Health Organisation regards them as a form of temporary disability. A throbbing, often unilateral headache lasts from several hours to days and may be accompanied by nausea or a combination of photophobia and phonophobia. In ~20% of cases it is preceded by an aura. Estimated to afflict 15% of Australians, migraines vary considerably in characteristics but are identifiable by internationally classified criteria. The causes of migraine are thought to include both cerebrovascular and neuronal mechanisms to which individuals are genetically or hormonally predisposed. Women are 2-3 times as susceptible as men, particularly during menstruation and perimenopausally, when migraine without aura may result from sudden changes in circulating estrogen, other hormones or prostaglandins. Hormone replacement therapy or phytoestrogen supplementation may help in some cases, although the evidence is weak and mechanisms are unclear. 

Owing to better therapies, patients with type 1 diabetes (T1D) are living longer and are now a unique population that has been little studied. Differing from type 2 diabetes (T2D), the onset of T1D is usually juvenile, but it is increasingly diagnosed in adulthood, requiring immediate insulin therapy. Regardless, T1D and T2D share a common sequelae of blood vessel damage and accelerated cognitive decline. Even children and adolescents with T1D display early declines in executive function and short-term working memory and impaired growth and plasticity of brain tissues, thereby compromising learning in school.

The left atrium (LA) is one of the four chambers of the heart. Its primary roles are to act as a holding chamber for blood returning from the lungs and to act as a pump to transport blood to the left ventricle of the heart, after which the blood flows to the body.

The Gene Pulser Xcell system is a modular electroporation system for transfecting every cell type.

This grant will support our eHealth research project measuring the impact of web-based feedback on dietary intake in improving eating patterns and health.

Fathers have a unique and key role in shaping their children's dietary and physical activity behaviors and emerging evidence suggests suboptimal physical activity and dietary behaviours of fathers may be passed on to their children at a very young age.

Following a cardiovascular event (e.g. heart attack) the heart undergoes significant physical changes, including an increase in scar tissue, changes in morphology and decreased functional capacity (heart remodelling).

Cardiac catheterisation and percutaneous coronary intervention (PCI) are commonly performed procedures to investigate and manage cardiac disease.

The Greaves Family Early Career Support grant will enure Myles Young can extend his research with the SHED-IT weight loss program to  achieve his goal of becoming an independent and internationally reputable early career researcher in the Hunter Region.

Diabetes is associated with significant risk of disease of both the large and small blood vessels.

The aim of my PhD is to investigate effective and innovative approaches to managing weight during pregnancy and following childbirth.

40% of all type 2 diabetics will develop diabetic nephropathy (DN), which is the leading cause of end stage kidney failure in Australia and around the world.

Type 2 Diabetes is the fastest growing chronic disease in Australia.

Digestive disorders remain a major health burden.

There has been considerable research into the use of exercise for the treatment of depression in adults, however the majority of research in adolescent major depressive disorder (MDD) over the past decade has focused on the efficacy of medications and cognitive behaviour therapy (CBT), with these methods only achieving rates of remission of 30% to 40% and high rates of relapse among those responding positively (Kennard et al., 2006).