Dr. Md Reduanul Hossain is an early-career researcher at the Global Centre for Gynaecological Diseases, School of Biomedical Science and Pharmacy. He completed his PhD in Reproductive Medicine at the University of Newcastle, Australia, under the supervision of Distinguished Laureate Professor Roger Smith and Dr Jonathan Paul, with a focus on preventing preterm birth.
During his PhD, Dr Hossain developed a uterine-targeted drug delivery system, a novel strategy designed to prevent preterm birth while enhancing the safety of therapeutic interventions for both the mother and the baby.
He conceived and conducted studies to optimise this nanomedicine platform for clinical use. By analysing biopsies of pregnant women’s uterine tissue, Dr. Hossain evaluated both established and new contraction-blocking drugs (tocolytics) to identify combinations that produce a synergistic effect, improving therapeutic outcomes with lower drug dosages.
He identified eight novel drug combinations that achieve these synergistic effects in inhibiting pregnant human uterine contractions. Currently, Dr. Hossain is working on encapsulating these drug combinations into the nanoparticle-based uterine-targeted drug delivery system. This advancement represents a significant leap forward in preterm birth prevention strategies, offering a safer and more effective approach to managing this critical issue.
