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Professor Nathan Bartlett

Professor Nathan Bartlett

Professor, University of Newcastle

Research Programs

Development of the first mouse model of rhinovirus infection and airways disease exacerbation,
Discovered that the stimulation of cell surface-expressed TLR2/6 induces sustained innate immune-mediated anti-viral protection in respiratory mucosa
Defined a new immune-regulatory role for IL-25 that directly inhibits virus induced airway epithelial cell innate anti-viral immunity

Professor Nathan Bartlett has dedicated over 20 years to viral immunology and the pathogenesis of virus-induced diseases, primarily viral asthma exacerbations.

He has developed and led the Viral Immunology and Respiratory Disease group (University of Newcastle, located in Hunter Medical Research Institute).

His work has made internationally important contributions and led to the development of new therapies currently in clinical trials. This has been achieved through a strong record of collaboration with clinical researchers and translational research.

This has positioned the group favourably to utilise a variety of integrated therapeutic approaches (viral vaccine vectors, innate immune modulators, antibody/nanobody-based therapeutics, RNA interference, nanomedicines and small molecule-based drugs) and models (primary bronchial epithelial cell air-liquid-interface culture, donated lung sections, mice models of respiratory disease).