Medical Research

Research Interests

• Dyspepsia and functional dyspepsia
• Eosinophilic gastrointestinal disorders
• Irritable bowel syndrome
• Gastro-oesophagal reflux disease and Barrett's oesophagus

Why did you get into research?

An endless fascination with the unexplained, and to address common clinical problems that need better management.

What would be the ultimate goal for your research?

Our goal is to find the causes of chronic unexplained gut diseases from dypepsia to irritable bowel syndrome, unlock new targets for therapies and ultimately cure disease.

Biography

Distinguished Laureate Professor Nicholas (Nick) Joseph Talley, AC, MD (NSW), PhD (Syd.), FRACP, FAFPHM, FAHMS, is a distinguished neurogastroenterologist, clinician and educator with a research interest in disorders of gut-brain interactions, intestinal inflammation including eosinophilic gastrointestinal disorders, and the intestinal mucosa-associated microbiome.
Nick is currently Professor of Medicine at the University of Newcastle, an NHMRC Leadership Fellow, and Chief Investigator of the NHMRC Centre for Research Excellence in Digestive Health in Newcastle. He is Emeritus Editor-in-Chief of the Medical Journal of Australia, and a past Editor of the American Journal of Gastroenterology and Alimentary Pharmacology and Therapeutics.
He has over 1000 peer-review publications, is highly cited (>143,000 cites, H-index 196, Google Scholar) and is considered an international authority in the field. Awards include a Companion of the Order of Australia (AC) for his contributions to medicine, NSW Scientist of the Year, and the Peter Wills Medal from Research Australia. Nick was previously Chair of the Department of Internal Medicine at Mayo Clinic Florida, and Professor of Medicine and Epidemiology. He is currently an Adjunct Professor at the University of North Carolina, and was a Foreign Guest Professor at the Karolinska Institute for 6 years. His undergraduate textbook Clinical Examination (now 9th edition) won 1st place in the British Medical Association Book Awards in 2018.

Specialised/Technical Skills

• Clinical research
• Epidemiology (clinical)
• Genetic epidemiology
• Clinical trails
• Questionnaire design and validation
• Biomarkers

Affiliations

• Professor of Medicine, Faculty of Health and Medicine, University of Newcastle
• Chair, Committee of Presidents of Medical Colleges (CPMC)
• Director, Priority Research Centre, Digestive Health and Neurogastroenterology
• Hon Treasurer, Australian Academy of Health and Medical Sciences
• Senior Staff Specialist, John Hunter Hospital, Newcastle, Australia
• Professor of Medicine and Professor of Epidemiology, Joint Supplemental Consultant Gastroenterology and Health
• Sciences Research, Mayo Clinic, Rochester, MN, USA
• Adjunct Professor, University of North Carolina, NC, USA
• Foreign Guest Professor, Karolinska Institutet, Stockholm, Sweden
• Past President, Royal Australasian College of Physicians