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Dr Md Reduanul Hossain

Dr Md Reduanul Hossain

Research Fellow, University of Newcastle

Research Programs

Dr Md Reduanul Hossain is a Research Fellow at the University of Newcastle and the Hunter Medical Research Institute (HMRI), with expertise in placental biology, extracellular vesicles, and uterine contractility. His research aims to advance the understanding of labour mechanisms and to develop innovative diagnostics and therapies for preventing preterm birth.

Dr Hossain completed his PhD in Reproductive Medicine at the University of Newcastle, where he explored combinational tocolytic therapies and engineered nanoliposome-based drug delivery systems targeting the uterus. He also holds MSc and MPhil degrees in pharmaceutical sciences from the University of Greenwich, UK.

His research spans two key translational areas: diagnostics and therapeutics. He is currently pioneering a “liquid placental biopsy” based on corticotropin-releasing hormone (CRH) mRNA-containing exosomes, exploring their role as early non-invasive biomarkers for labour prediction. His work challenges traditional endocrine paradigms by proposing that placental exosomes deliver functional CRH mRNA directly to myometrial cells, modulating uterine contractility. In the therapeutic domain, Dr Hossain is developing uterine-targeted nanoparticles to deliver novel synergistic drug combinations aimed at safely delaying labour.

He has published in Reproductive Sciences, presented at international conferences, and secured competitive funding from the John Hunter Hospital Charitable Trust and BorneHMRI.

Dr Hossain collaborates closely with clinicians, perinatal researchers, and bioengineers to translate laboratory discoveries into real-world maternal health solutions. His long-term goal is to reduce preterm birth and stillbirth, particularly among vulnerable populations, by integrating precision diagnostics and targeted treatment strategies into clinical practice.